We are pleased to announce the 3rd CASUS Annual Workshop with this year’s topic “Digital Twins of Complex Systems”.

The event takes place online from 6 – 9 December 2021.

The conference will be held in English.

Registration is open until 28 November. Please register here.


Digital twins represent the next step in our understanding of complex technical and natural systems. They represent a digital replica of real-life systems on all scales in structure, interactions and evolution over time.

Digital twins are more than models of reality, as they include direct inclusion of sensors and measurements and provide live feedback to their environment and include intelligent systems that interact with the real world. Digital twins thus break the boundary between the pure digital sphere and our daily experience.

Realizing digital twins of complex systems requires utilizing cutting-edge technologies. In this workshop we address the challenges of developing digital twins across scientific domains and in industry, showcasing the most promising approaches and discussing future prospects. We aim for sharing best practices and discuss the potential of technology solutions that cross the boundaries between application areas.

Application areas include but are not limited to Earth Systems Science, Materials Research, Research Infrastructures, Biological Systems, Digital Health, Energy Systems, Digital twins in industry, and more.

The workshop features key technology areas such as Exascale Computing, Human Machine Interaction, Machine Learning, Artificial Intelligence, Real Time Analytics and Feedback, Intelligent Infrastructures, Simulations, Visual Analytics, Streaming I/O, Scalable Online Analysis, Edge Computing, IoT, Autonomous Systems, and more.

Topics of the workshop include

  • Fusion of data from sensors, experiments, measurements and simulations
  • Close to real time data integration and data stream incorporation from multiple data sources
  • Multi-scale, multi-disciplinary modeling and co-simulation capabilities scalable towards realistic high-resolution complex digital twins
  • Interactive and intelligent analysis of the dynamical behavior of digital twins and seamless exploration of the complete digital twin
  • Availability of mathematical methods and algorithms for multi-scale simulations, scalable numerical algorithms, agent- and graph-based approaches, network science and complex systems research

Communication and video platform

We will use zoom for the online video conference. We will send the speakers and registered participants a link to the conference room. Detailed information about how to use zoom you can find here.

Confirmed speakers

Tjalf Ziemssen, Center of Clinical Neuroscience, TU Dresden: “Digital twin in healthcare: the use case multiple sclerosis”

Jaroslaw Harezlak, Department of Epidemiology and Biostatistics, Indiana University: “Influence of head impact exposure on sport-related concussions: functional data analytic approach

Thomas Neumuth, Innovation Center Computer Assisted Surgery (ICCAS), University of Leipzig: “Digital patient twins and model-based medicine

Frank Dressel, Acting Head of Department, Institute of Software Methods for Product Virtualization, Software Methods, DLR: “How to trust digital twins

Nils Wedi, Head of Earth System Modelling, ECMWF: “Destination Earth and digital twins of the earth system

Olga Fink, Professor of Intelligent Maintenance Systems, ETH Zürich: “Hybrid operational digital twins for complex systems: Fusing physics-based and deep learning algorithms for fault diagnostics and prognostics

Provisional schedule

Time Topic
Monday, 6 December 2021
15:00 – 15:30 CEST Registration and technical test
15:30 – 15:40 CEST Welcome address by Director of CASUS
15:40 – 16:15 CEST Opening keynote by Scientific Head of CASUS
16:15 – 17:00 CEST Talk
17:00 – 17:10 CEST Bio break
17:10 – 18:00  CEST Talk
Time Topic
Tuesday, 7 December 2021
15:15 – 15:30 CEST Registration and technical test
15:30 – 17:00 CEST Talks
17:00 – 17:15 CEST Coffee break
17:15 – 18:00 CEST Talks
Time Topic
Wednesday, 8 December 2021
15:15 – 15:30 CEST Registration and technical test
15:30 – 16:30 CEST Talk keynote speaker (tba)
16:30 – 17:30 CEST Panel
Time Topic
Thursday, 9 December 2021
15:15 – 15:30 CEST Registration and technical test
15:30 – 17:00 CEST Talks
17:00 – 17:15 CEST Coffee break
17:15 – 18:00 CEST Talks

Information about the CASUS Annual Workshop 2020 “Fusing Artificial Intelligence & Simulation”

Video playlist from CASUS Annual Workshop 2020

CASUS Annual Workshop scientific organizing committee

Prof. Dr. Roland Sauerbrey, Founding Director of CASUS, Helmholtz-Zentrum Dresden-Rossendorf
Dr. Michael Bussmann, Scientific Head CASUS, Helmholtz-Zentrum Dresden – Rossendorf
Prof. Dr. Sabine Attinger, Head of Department of Computational Hydrosystems (CHS), Helmholtz Centre for Environmental Research – UFZ
Prof. Dr. Wolfgang E. Nagel, Director of the Center of Information Services and High-Performance Computing (ZIH), Technische Unversität Dresden
Prof. Dr. Ivo F. Sbalzarini, Chair of Scientific Computing for Systems Biology MOSAIC Group, Max Planck Institute of Molecular Cell Biology and Genetics
Prof. Dr. Małgorzata Bogdan, Institute of Mathematics, University of Wrocław